In this week's episode, we explore the quest for a therapy that not only alleviates symptoms of osteoarthritis but also addresses the underlying disease process. Host Professor David Hunter is joined by Chris Knight and Dr Sandeep Basnet from Formation Bio to discuss the complexities and breakthroughs in developing disease-modifying osteoarthritis drugs (DMOADs).

They dive into the challenges of clinical trials, the high stakes of drug development, and the promising future of AI in revolutionising this field.

Tune in to learn how close we are to seeing these game-changing therapies become a reality and what it could mean for millions living with osteoarthritis.

RESOURCES

Formation Bio: https://www.formation.bio/

CONNECT WITH US

• Twitter/X: @ProfDavidHunter @jointactionorg
• Instagram: @ProfDavidHunter
• Email: hello@jointaction.info

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This week on Joint Action, we explore the potential of natural ingredients in relieving knee osteoarthritis pain. We start with a short introduction to the ATLAS study, a clinical trial by Professor David Hunter and a team of researchers at The University of Sydney. The ATLAS study is testing a groundbreaking supplement combining curcumin, boswellia serrata extract, and more. Can this blend offer pain relief for people with knee osteoarthritis? To learn more or be part of the study, visit: www.osteoarthritisresearch.com.au/atlas-study-overview

To help unravel the complexities of supplements and complementary medicines for osteoarthritis, we welcome Dr. Joanna Harnett, a Senior Lecturer at the University of Sydney's School of Pharmacy. Dr. Harnett discusses the most commonly used supplements for osteoarthritis, the evidence supporting their use, and important safety considerations. She also provides practical advice on selecting the right complementary medicine and emphasizes the importance of consulting healthcare providers.

Whether you're curious about natural supplements or looking for guidance on managing osteoarthritis, this episode offers valuable insights to help you make informed decisions.

RESOURCES

• ATLAS study: www.osteoarthritisresearch.com.au/atlas-study-overview

Journal articles

• Which supplements can I recommend to my osteoarthritis patients?
• Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis
• Managing Dietary Supplements and Complementary Medicines in Osteoarthritis

CONNECT WITH US

• Twitter: @ProfDavidHunter @jointactionorg
• Email: hello@jointaction.info
• Website: www.jointaction.info/podcast

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In this episode of the Joint Action podcast, we explore how injuries to the ACL (anterior cruciate ligament) in the knee can lead to osteoarthritis, especially in young people aged 15-25. Did you know that up to 20% of people who develop knee osteoarthritis do so because of a past injury? ACL injuries are a major culprit, and their impact can be life-changing.

We chat with Dr Andrew Ross, a physiotherapist and researcher, and Associate Prof Chris Schilling, a health economist, about how we can prevent these injuries in the first place. They share insights from recent studies showing that national injury prevention programs could save millions in healthcare costs, improve quality of life, and keep more people active in sports for longer.

We also discuss the challenges of getting these programs off the ground and why they’re so crucial - not just for individual athletes but for society as a whole. If you’re interested in how we can better protect our knees and prevent osteoarthritis, this episode is a must-listen!

RESOURCES

Previous episodes

• Knee injury and osteoarthritis with Tim Hewett
• Is osteoarthritis preventable? with Dr Jackie Whittaker

Programs

• Perform+
• FIFA 11+ Program
• GLAD Australia

Papers

• The economics of a national anterior cruciate ligament injury prevention program for amateur football players: a Markov model analysis
• The time is right to do more to reduce ACL injuries

CONNECT WITH US

• Twitter/X: @ProfDavidHunter @jointactionorg
• Instagram: @ProfDavidHunter
• Email: hello@jointaction.info

Hosted on Acast. See acast.com/privacy for more information.