Biology Genetics

Scientists' understanding of life is progressing more rapidly than at any point in human history, from the extraordinary decoding of DNA to the controversial emergence of biotechnology. Featuring pioneering biologists, geneticists, physicists, and science writers, Life explains just how far we've come - and takes a brilliantly educated guess at where we're heading.

Australopithecines, dinosaurs, trilobites - such fossils conjure up images of lost worlds filled with vanished organisms. But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty.

In Origins, Frank H. T. Rhodes explores the origin and evolution of living things, the changing environments in which they have developed, and the challenges we now face on an increasingly crowded and polluted planet. Rhodes argues that the future well-being of our burgeoning population depends in no small part on our understanding of life's past, its long and slow development, and its intricate interdependencies.

First coined by Richard Dawkins in The Selfish Gene, a meme is any idea, behavior, or skill that can be transferred from one person to another by imitation. Susan Blackmore shows that once our distant ancestors acquired the crucial ability to imitate, a second kind of natural selection began, a survival of the fittest amongst competing ideas and behaviors. Ideas and behaviors that proved most adaptive-making tools, for example, or using language - survived and flourished, replicating themselves in as many minds as possible.

Named one of the top books of 2009 by the Times Literary Supplement (London), this controversial and compelling audiobook from Dr. Stephen C. Meyer presents a convincing new case for intelligent design (ID) based on revolutionary discoveries in science and DNA. Along the way Meyer argues that Charles Darwin's theory of evolution as expounded in The Origin of Species did not, in fact, refute ID.

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

In Survival of the Prettiest, Nancy Etcoff, a faculty member at Harvard Medical School and a practicing psychologist at Massachusetts General Hospital, argues that beauty is neither a cultural construction, an invention of the fashion industry, nor a backlash against feminism - it's in our biology.

The study of human evolution is advancing rapidly. Newly discovered fossil evidence is adding ever more pieces to the puzzle of our past, while revolutionary technological advances in the study of ancient DNA are completely reshaping theories of early human populations and migrations. In this Very Short Introduction, Bernard Wood traces the history of paleoanthropology from its beginnings in the 18th century to the very latest fossil finds.

There is no one better qualified than Jared Diamond - renowned expert in the fields of physiology and evolutionary biology and award-winning author - to explain the evolutionary forces that operated on our ancestors to make us sexually different. With wit and a wealth of fascinating examples, he explains how our sexuality has been as crucial as our large brains and upright posture in our rise to human status.

Humans are a puzzling species. On the one hand, we struggle to survive on our own in the wild, often failing to overcome even basic challenges, like obtaining food, building shelters, or avoiding predators. On the other hand, human groups have produced ingenious technologies, sophisticated languages, and complex institutions that have permitted us to successfully expand into a vast range of diverse environments. What has enabled us to dominate the globe, more than any other species, while remaining virtually helpless as lone individuals?

The Origin of Humankind is Richard Leakey's personal view of the development of Homo sapiens. At the heart of his new picture of evolution is the introduction of a heretical notion: Once the first apes walked upright, the evolution of modern humans became possible and perhaps inevitable. From this one evolutionary step comes all the other evolutionary refinements and distinctions that set the human race apart from the apes.

Everywhere there are characteristics of animals that do not want to fit into the theory of evolution anywhere. And man? Are we really the most adapted life-form on this planet? Today, more and more scientists who contradict the previous theory of evolution speak out. The theory fits the changes within the species, but it can no longer be reconciled with the inner workings of the cell. Some other influence that has so far escaped us is affecting evolution. It is called "Intelligent Design." Intelligent planning is suspected behind this.

For most of us, the story of mammal evolution starts after the asteroid impact that killed the dinosaurs, but over the last 20 years, scientists have uncovered new fossils and used new technologies that have upended this story. In Beasts Before Us, paleontologist Elsa Panciroli charts the emergence of the mammal lineage, Synapsida, beginning at their murky split from the reptiles in the Carboniferous period, over 300 million years ago. They made the world theirs long before the rise of dinosaurs.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections.

At once a spirited defense of Darwinian explanations of biology and an elegant primer on evolution for the general listener, What Evolution Is poses the questions at the heart of evolutionary theory and considers how our improved understanding of evolution has affected the viewpoints and values of modern man.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.